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In addition, toxic or pathologic conditions that lead to an impairment of mitochondrial function can increase the release of ROS

Magnesium is an essential mineral known for its numerous health benefits

Corticosteroids promote: Fat redistribution , causing central (truncal) obesity and the characteristic "cushingoid" appearance with prolonged use Fluid retention , leading to weight gain that may not reflect true fat accumulation but can be discouraging Muscle protein breakdown , reducing lean body mass and potentially lowering metabolic rate Insulin resistance , making weight loss more difficult The magnitude of these effects is generally dose- and duration-dependent

Therefore, there are limited clinical trial data with semaglutide use in pregnant women

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