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Tirzepatide (Zepbound) is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity
Restoration of the HPG axis through weight loss addresses these symptoms at the hormonal root rather than through symptomatic treatment
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