With the FDA declaring the tirzepatide shortage resolved as of early 2025, the landscape for compounded or DIY versions has changed
other cardiac glycosides (eg, oleander, foxglove)Consult with poison center regarding dosing, especially for cardiac glycosides other than digoxin8 and 24 hours: 15 vialsImmediate emergency departmentDMSA (Succimer)/ ChemetHeavy metal poisoning (lead, mercury, arsenic) 8 hours: 1 g or 10 x 100 mg capsules24 hours: 3 g or 30 x 100 mg capsules DTPA-Calcium (Diethylenetriamine pentaacetate)/ (Pentetate Calcium Trisodium injection)Dirty bomb agents: radioactive plutonium, americium and curiumOnly available through government sources
Relevance to humans remains uncertain
Wegovy (semaglutide injection) is FDA-approved for: Chronic weight management in adults with a BMI of 30+ (obesity), or BMI of 27+ with at least one weight-related condition (e.g., high blood pressure, type 2 diabetes, or high cholesterol) Weight management in adolescents aged 12 and older with obesity (initial body weight 60 kg) Reducing cardiovascular risk lowering the risk of heart attack, stroke, or cardiovascular death in adults with established cardiovascular disease who are also overweight or have obesity Wegovy is meant to be used alongside a reduced-calorie diet and increased physical activity, not as a standalone treatment
Mo Cale, a board-certified physician and Medical Director of Center for Confidence, where Ive helped countless patients steer peptide therapies including GHRP 2 fat loss protocols as part of comprehensive hormone optimization and body recomposition programs
