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The impact of radiation on SLC7A11 activity and GSH levels leads to the accumulation of lipid peroxides and the initiation of ferroptosis

Thats really what is driving this research program.

When superposing a predicted model of full-length CTL1 on our experimentally determined CTL1 model, the prediction helps to approximate where unmodeled regions of the extracellular domain and M3/M4 protrude from the micelle, matching the map when displayed at a lower contour level (Fig 4C)

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