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[231] when triggered by amphetamine, this pathway activates Ras homolog A (RhoA) and its downstream protein kinase, Rho-associated coiled-coil kinase (ROCK), an effect that internalizes both DAT and the neuronal glutamate transporter EAAT3

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10.1016/j.plipres.2018.06.002 Prog Lipid Res

Therefore, we always recommend consulting with our healthcare providers for a more accurate estimate