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Abstract Copper-containing enzymes perform fundamental functions by activating dioxygen (O 2 ) and therefore allowing chemical energy-transfer for aerobic metabolism

(13) Preclinical studies have demonstrated that GLP-1 receptor agonists like exenatide can enhance bone mass in diabetic and insulin-resistant rat models by upregulating OPG expression and improving the OPG/RANKL ratio

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Tyuryaeva et al., 2023)