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While GLP-1 RAs offer promising therapeutic outcomes, clinicians must address potential challenges, including gastrointestinal side effects, contraindications (e.g., pregnancy, severe GI disorders), and risks associated with improper compounding practices (48)(540)

Glucagon-like peptide-1 (GLP-1) and the regulation of human invariant natural killer T cells: lessons from obesity, diabetes and psoriasis

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It is careful to say awareness of the risk does not preclude GLP-1 use, and that the practical takeaway is the importance of a baseline eye assessment before starting rather than avoiding treatment altogether

Peptide therapeutics have evolved from single-receptor targets to dual-agonists, each stage offering new opportunities in metabolic regulation