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A seven-year study with nearly 120,000 participants found GLP-1s were associated with lower rates of new prostate cancer diagnoses in high-risk men, compared to drugs such as Merck's Propecia and GSK's Avodart, which are used to shrink enlarged prostate glands
The scientists found that with linkers that were too short, the GLP-1 would either not bind the HSA strongly enough and it would have a very short lifetime in the body, or alternatively, if they were too long, the HSA would bind too strongly so that it wouldnt be released when needed
Emerging new candidates are the receptor agonists of the incretin hormone glucagon-like-peptide-1 (GLP-1), originally used for the treatment of diabetes
Comparison of the efficacy of MOE and PMO modifications of systemic antisense oligonucleotides in a severe SMA mouse model
Benefits include reduced wrinkles , improved skin texture, enhanced hair growth , and accelerated healing
