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doi: 10.3389/fendo.2019.00778

e-SPEN Journal 2014

Semaglutide and tirzepatide reduced blood glucose by ~200 mg/dL and HbA1c by ~2% at 2 months, but their effects waned by the third month

It works in three key ways: Appetite suppression Semaglutide mimics GLP-1, a hormone that slows digestion and signals fullness, helping reduce cravings and portion sizes