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For instance, Amgens pipeline includes an amylin analog (AMG 135) with monthly potential, likely to be combined with their GLP-1 for greater efficiency

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It represents the first clinically advanced compound of the triple-incretin agonist class

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"We can see very clearly that this is specific to medications that are working through GLP-1 receptor pharmacology." Two additional clinical trials funded by pharmaceutical companies showed no difference between carriers and non-carriers, although these studies used longer-acting GLP-1 drugs

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