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However, the insulinotropic effect of incretins is diminished in type 2 diabetic patients, due in part to reduced expression of incretin receptors as a consequence of glucotoxicity

This variability likely reflects differences in study populations, such as the presence or absence of T2DM, degree of obesity, sex distribution, and comorbid conditions, as well as differences in intervention characteristics, including the type, dose, and duration of GLP-1 RA therapy

Individuals on oral diabetes medications, particularly sulfonylureas, face increased hypoglycemia risk when combined with GLP-1 therapy, requiring dose adjustment or medication switching

View current TeleHealth Med GLP-1 program details (Link directs to a partner referral page

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