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56 The NMR solution structure of the complex reveals a core , cross-brace fold with a 1,3,2 antiparallel -sheet arrangement, in which the outer 2 strand hydrogen bonds with the ZNG1-derived peptide (Figure 50B)

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placebo with insulin) showed significant A1C reduction, weight loss, and improved cardiovascular markers

Lentivirus was produced by transfecting HEK293T cells plated in a T75 flask with 6 g of psPAX2, 3 g of pMD2.G and 12 g of lentiviral vector containing the LaccID, TCR or CAR with 60 l of PEI Max (1 mg ml 1 in water, pH 7.3)