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Description

Cells were treated with dTAG-v1 or DMSO, and cell viability was assessed either indirectly, by measuring metabolic activity of mitochondrial dehydrogenases by WST assay (Fig

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& Padi, M

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This means having a BMI of 30 or higher or a BMI of 27 or higher with weight-related health conditions

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As with CYP2E1, there are substantial inter-ethnic differences in CYP2D6 across populations, ranging from complete loss of function or reduction in functional activity (2570% of the population, dependent on ethnic origin and geographical location) to extensive, ultra-rapid metabolisers (1.59.3% of the population) (see Table 3 in the supplementary data for a summary of the evidence) [17, 38]

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98 It is not surprising that aging and cancer are two linked processes

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