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b) condensing Fmoc-Leu-V al-Arg(pbf)-Gly-Arg(pbf)-Gly-OtBu (fragment-5) with Fmoc- Gln(Trt)-Ala-Ala-Lys(PEG-PEG-y-Glu-octadecane dioic acid)-Glu (OtBu)-Phe-Ile-Ala- Trp(Boc)-OH (fragment-4) in presence of a coupling agent, followed by deprotection in presence of a base to obtain 15 amino acid peptide chain