However, the magnitude of some of these observational estimates (for example, relative reductions in cardiovascular or all-cause mortality exceeding 50%) is considerably larger than would be predicted from the randomized effect sizes of either class and is almost certainly inflated by residual and time-related confounding, including healthy-adherer and prevalent-user biases
Overall, the brand is seen as a gamble rather than a reliable solution
70% of Indian women with PCOD dont respond to diet and exercise alone. Indian Endocrinology Review, 2023 GLP-1 therapies have shown 1520% body weight loss over 12 months, outperforming diet and exercise alone. NEJM, 2021 Non-surgical medical weight loss treatment in Delhi and across India refers to clinically supervised, evidence-based programs designed to support sustainable fat reduction and improved metabolic health without surgery, incisions, or prolonged recovery
Yet pricing confusion keeps many people from accessing these medications
Furthermore, these drugs are not a panacea for the obesity epidemic, as comprehensive solutions must also address underlying behavioral, social, and environmental factors