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Nat Rev Gastroenterol Hepatol 14:110121 Sobczak M, Fabisiak A, Murawska N, Wesoowska E, Wierzbicka P, Wlazowski M, Wjcikowska M, Zatorski H, Zwoliska M, Fichna J (2014) Current overview of extrinsic and intrinsic factors in etiology and progression of inflammatory bowel diseases