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In laboratory and animal studies, GLP-1 receptor agonists appear to reduce production of pro-inflammatory cytokines, including tumor necrosis factor-alpha (TNF-), interleukin-6 (IL-6), and interleukin-1 beta (IL-1)

Compounded semaglutide contains the same active ingredient as the brand-name versions

For instance, the gastrointestinal side effects commonly associated with Mounjaroparticularly severe or persistent vomiting and diarrhoeacould potentially lead to mucosal irritation or, in rare cases, oesophageal tears (Mallory-Weiss tears) that might result in bleeding

Carmot is developing CT-388, a GLP-1/GIP receptor agonist

GLP-1 is also linked to how the brain processes reward and pleasurable stimuli, he said