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This goes to show that maintaining a healthy weight can positively impact IGF-1 levels, potentially improving overall metabolic health while aiding in muscle growth and recovery: This study aimed to characterize the association between serum insulin-like growth factor-1 (IGF-1) and obesity, as well as fat distribution, before and during moderate energy restriction (1,200 kcal/d)

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[DOI] [PubMed] [Google Scholar] 115.Senanayake G.V., Banigesh A., Wu L., Lee P., Juurlink B.H

2 Veyssiere et al., PNAS (2015)Retro-inverso and short spadin analogs (including PE-22-28) as optimized TREK-1 blockers with antidepressant activity in mice