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[2,7] Rebound Effect: After stopping the medications without changing habits, people commonly regain up to two-thirds of the lost weight within the first year

[5] [6] The fundamental difference is critical: prescription medications like semaglutide 2.4 mg (Wegovy) and tirzepatide (Zepbound) produce substantial, dose-dependent increases in receptor activation with clinical trial evidence showing approximately 15% and up to 21% body weight reduction, respectively

A healthcare professional may recommend taking certain supplements if youre taking GLP-1 medications

Ozempic and Mounjaro are drugs in the glucagon-like-peptide-1 (GLP-1) receptor agonist drug class

But the real buzz around these drugs grew as it became clear they could also be used as weight loss medications