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Hypoglycemiablood glucose below 70 mg/dLoccurs most commonly in patients using semaglutide in combination with insulin injections or sulfonylurea drugs like glyburide or glipizide

However, tirzepatide Seattle targets two hormone receptors, the GLP-1 and GIP, while semaglutide only targets the GLP-1

2d and e) in a model of I/R injury [26]

Table of Contents Understanding GLP-1 Therapy in Type 1 Diabetes Potential Benefits and Clinical Outcomes Risks, Safety Concerns, and Limitations Patient Selection and Practical Considerations Understanding GLP-1 Therapy in Type 1 Diabetes GLP-1 receptor agonists are well established in type 2 diabetes, yet their role in type 1 diabetes remains off-label