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Fatty Acid Acylation and Albumin Binding Pharmacokinetics Source: PubMed PMID: 26308095 Summary: This medicinal chemistry study described the design and structure-activity relationships of GLP-1 analogs with C-18 fatty diacid modifications

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Existing anti-diabetic drugs contribute towards improving glycemic control by either increasing the bodys sensitivity to insulin, enhancing insulin secretion or reducing renal glucose reabsorption

The test examines genetic variants like GLP1R rs6923761 and GIPR rs1800437 that affect peptide sensitivity and medication response

these effects are generally dosedependent