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Insulin resistance is one of the contributing factors for many diabetics
By the time the next dose increase occurs, many patients have adapted to the current dose and the cycle begins again at a manageable level
Although exceedingly uncommon (0.03 cases per 1,000 patient-years), MALA carries a high mortality rate (50%) (Wang et al., 2021)
Freezing reconstituted peptides is not recommended for regular use because freeze-thaw cycles cause aggregation and loss of activity
Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer
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