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For how I adapted fueling on race day, see my race day fueling guide

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Why the Glucagon Receptor Is the Game-Changer Both semaglutide and tirzepatide produce weight loss primarily through appetite suppression and improved insulin signaling

Physical Activity Weight loss is most sustainable when it includes some form of movement

The ADA/EASD consensus on glycaemic management algorithm already includes GLP-1 receptor agonists with cardiovascular benefit as an option for people with CKD when SGLT2 inhibitors are contraindicated or not tolerated, in order to reduce the risk of cardiovascular disease (Davies et al, 2022)