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We chose to make all transport rates linear and adjusted them so that the measured APAP, APAP-S, APAP-G, and NAPQI-GSH concentrations in the plasma and the urine were as measured in the literature[4, 6, 11, 3032]

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Discuss how patients source their medicines especially as standard supplies maybe unavailable, costly, resulting in use of unlicensed pharmacies or skipped doses