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Endocr Rev 23 : 824854 Monzavi R and Cohen P (2002) IGFs and IGFBPs: role in health and disease

The ideal B12 supplement contains a mix of methylcobalamin, hydroxocobalamin and adenosylcobalamin (11)

One study of 48 children (mean age 7 years and 4 months) with ASD and language impairment split patients into two groups, one received 2mg/kg/day (up to 50mg max) leucovorin calcium (folinic acid calcium salt), the other received placebo

Common symptoms include: Constant fatigue Weakness Pale skin Tingling or numbness Difficulty walking Memory problems Poor concentration Mood changes Mouth ulcers Breathlessness Loss of appetite Severe deficiency requires prompt medical evaluation

Weight loss peptides might be taxed differently from peptides used in performance or anti-aging