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During alkali injury, the corneal oxidative stress response is significantly enhanced, lipid peroxidation occurs, a large amount of intracellular iron ions accumulate, and the activity of GPX4 decreases (54)

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Mean NADP+ ( A ) and NADPH ( B ) levels in A549shNRF2-BIND-luc cells treated with water (Control) or 2.5 ng/mL doxycycline (Dox) for 48 h

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There are trade-offs

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This often restores first-phase insulin secretion and production, helping to prevent blood sugar spikes after meals

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11c and Fig

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