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Review of the history and milestones in GLP-1 research In 1979, Richard Goodman found that anglerfish are an ideal source for pancreatic mRNA due to their concentrated cells

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Studies have suggested that the N-terminal residues His7, Gly10, Phe12, Thr13 and Asp15 are essential for interaction with the GLP-1 receptor, as substituting these residues with L-Ala leads to a severe loss of affinity for its receptor [43]

Graphical Abstract Similar content being viewed by others Introduction The incidence and prevalence of type 1 diabetes is increasing