glp 1 effect on fertility GLP-1 Medications and Fertility: What the Science Says — Natalie Crawford MD Current evidence does not show

OctNov 2025:9(1):1,bvaf149.119

Preclinical models indicate that GLP-1 receptor activation can influence the gut-brain axis as well as the hypothalamic-pituitary-adrenal (HPA) axis, with possible implications for stress regulation and energy homeostasis[11]

These non-animal strategies are faster, cheaper and provide extensive and meaningful data regarding both compounds hazard and safety and are constantly evolving and improving

January 2025: The defendants in the MDL have filed a new motion to dismiss many of the claims made in the plaintiffs master complaint

The study authors did a commendable job bolstering the case that this was a good apples to apples comparison by first comparing only people getting new diabetes medication, then statistically controlling for a whole range of other sociodemographic factors (age, education, race/ethnicity, area-level income) and MANY baseline health characteristics and health behaviors