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Nonclinical studies in rodents of clinically relevant doses of GLP-1 receptor agonists showed dose-related and treatment-duration-dependent increases in the incidence of thyroid C-cell tumors (adenomas and carcinomas)

doi: 10.1007/s10753-013-9616-0 188 AhmedSRiegseckerSBeamerMRahmanABelliniJVBhansaliPet al

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In a nationwide observational Swedish study (2006-2023), people with alcohol use disorder who also had obesity or type 2 diabetes had a lower risk of being hospitalized for alcohol use disorder when they were taking Semaglutide (Ozempic, Wegovy, Rybelsus) or Liraglutide

Phenobarbital will function synergistically with benzodiazepines, which could promote excessive sedation