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That evidence gap does not mean the combination is safe

As described in the Regulatory Impact Analysis for the CY 2026 PFS proposed rule (90 FR 32817), by potentially reducing shared savings payments to outliers with sharp growth in beneficiary assignment during the agreement period despite benchmark year beneficiary assignments dropping below the current 5,000-beneficiary minimum, the program may see additional net savings to the Medicare Trust Funds as compared to the current policy

You do not need a prescription for most vitamin B12 injections

There is no definitive consensus in the research community on optimal timing

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