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[13] Physiological vitamin D sufficiency is vital for placental function, foetal bone accretion, and maternal skeletal health, yet professional bodies caution against parenteral megadose therapy during uncomplicated gestation, preferring daily or weekly oral regimens that allow tighter titration and minimise abrupt calcium flux

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In the Phase 2 study, 12.2-18.2% of participants discontinued due to adverse events, depending on the dose group

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