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CysteineGSH axis in fibrosis control GSH, a key intracellular antioxidant, is synthesized from glutamate, cysteine, and glycine, with glutamatecysteine ligase (GCL) catalyzing the rate-limiting step[119]

Wegovy works best when combined with healthy lifestyle changes, explains Andrew Shapiro, MD, surgeon at Advanced Surgical Physicians and the medical director of the Comprehensive Breast Center at Wellington Regional Medical Center

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In a separate editorial, Holden Thorp, the publications editor-in-chief, noted that these drugs have raised more questions than they have answereda hallmark of a true breakthrough.[1] More research is needed into the potential side effects of the long-term use of these drugs, for example, and fears are growing that patients will abuse GLP-1 agonists, taking them when they arent clinically necessary

Side effects, when they occur, are usually mild gastrointestinal symptoms that ease over time