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Vitamin B12 deficiency is most common in adults over 50, vegans and vegetarians, pregnant women, and those with chronic health conditions like Crohns disease, inflammatory bowel disease (IBS), or rheumatoid arthritis

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Nature 458:762765 Galan-Cobo A, Sitthideatphaiboon P, Qu X et al (2019) LKB1 and KEAP1/NRF2 Pathways cooperatively promote metabolic reprogramming with enhanced glutamine dependence in KRAS-mutant lung adenocarcinoma

The variable R group gives rise to the four most commonly known cobalamins: cyanocobalamin (CNCbl), methylcobalamin (MeCbl), adenosylcobalamin (AdCbl, also known as cobamamide or 5-deoxyadenosylcobalamin), and hydroxocobalamin (OHCbl)

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