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In addition to intrinsic apoptosis, oxidative stress may also contribute to extrinsic apoptosis in vitiligo

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The inclusion criteria emphasized the following: (1) Mechanistic studies that explore NACs neuromodulatory effectsspecifically its impact on oxidative stress, neurotransmission, and neuroinflammatory signalingin both in vitro and in vivo models

10.1053/j.gastro.2015.03.045