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Baseline characteristics before GLP-1 RA treatment including age, gender, duration of diabetes mellitus, body mass index (BMI), serum creatinine, alanine aminotransferase, fasting plasma glucose, glycohemoglobin (HbA1c), C-peptide, lipid profiles, urine albumin-to-creatinine ratio (UACR) and concurrent antidiabetic medication use were recorded

Koia uses a combination of organic cane sugar (adding three grams of sugar) and monk fruit extract to sweeten the shake, resulting in a smooth flavor without an overly sugary or artificial taste

But the right dose and how often to give it depends on the patient

doi: 10.1097/PAS.0b013e318057faa7 86 FerraraGDe VannaAC

Rybelsus works by mimicking the action of the naturally occurring hormone GLP-1, which stimulates insulin secretion in response to food intake, suppresses glucagon release (a hormone that raises blood sugar), and slows gastric emptying