Hong F, Tuyama A, Lee TF, Loke J, Agarwal R, Cheng X, Garg A, Fiel MI, Schwartz M, Walewski J, Branch A, Schecter AD, Bansal MB
Barake M, Arabi A, Nakhoul N, et al
A better understanding of the various processes that modulate the interactions between the nervous system, the skin and immune components will likely contribute at identifying and developing new therapeutic strategies against HSV-1 infections and limit the burden caused by this virus on human health
The tumor microenvironment (TME) is composed mainly of tumor cells, stromal cells, immune cells and the extracellular matrix, which assume the functions of material exchange, environmental stress and immune regulation (69)
However, it is rapidly degraded by dipeptidyl peptidase-4 (DPP-IV) and other serum proteases, giving it a half-life of only 10-20 minutes