is glutathione bad for cancer Glutamine Glutathione-mediated nanomedicines for cancer diagnosis

showed that intracellular glutamate accumulation following cyst(e)ine depletion or system x C - inhibition is a key contributor to the induction of ferroptosis, and glutamate toxicity can be alleviated by converting excess glutamate to -glutamyl-di- or tripeptides via promiscuous enzymatic activities of glutamate-cysteine ligase catalytic subunit (GCLC) 12

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DNA was isolated from GSH-depleted and NAC treated cells after treatment with different doses of ASA as described in the Materials and Methods