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That is not a small shift

Dehydration can lead to hard, dry stools that are difficult to pass, increasing the likelihood of straining and rectal bleeding

[6] [5] Common adverse effects include gastrointestinal symptoms such as nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation

Thats why its important to eat nutritionally dense foods like fruits, vegetables, and whole grains

Further research is needed to directly assess the comparative effectiveness and cost-effectiveness of combination therapy using each drug class individually, including the newer agents, semaglutide and tirzepatide