However, case studies have reported serious side effects, such as bleeding and pain
A 2022 systematic review found that omega-3 supplementation or dietary intake was associated with improved oocyte quality in women undergoing ART, evaluated by both morphological and morphokinetic parameters. Animal studies show that omega-3 rich diets prolong reproductive lifespan and improve oocyte mitochondrial dynamics. Good dietary sources include oily fish (salmon, mackerel, sardines), walnuts, chia seeds, and flaxseeds
Interestingly, unlike other trials with TNF inhibitors, concomitant use of methotrexate appeared to produce greater protection from structural progression in this study
Therefore, researchers across the world felt the need to understand how antioxidant enzymes, including seleno-GPxs, being the primary ROS detoxification machinery, modulate cellular radiosensitivity
In another review worth noting, the meta-analysis consolidated findings across 15 cohorts (23 publications) evaluating the impact of flavan-3-ols intake on cardiometabolic outcomes (Reference Raman, Avendano and Chen7)