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With the World Cup on, my family has been glued to the television more than usual this summer

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Both tizanidine and tramadol can cause central nervous system depression, and these effects become amplified if you combine them, says Arthur Shektman MD, a board-certified plastic surgeon at the Gynecomastia Center of Boston who often prescribes tramadol for post-surgical pain

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The crucial question remains whether these benefits are sustainable over time and if the medication is safe for prolonged use