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Patients with a first-degree family history of BRCA-associated breast/ovarian cancer, Lynch syndrome-related colorectal cancer, or familial adenomatous polyposis should be counseled that the VEGF-stimulating profile of BPC-157 has not been studied in genetically high-risk populations

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Low B12 levels contribute to increased levels of homocysteine, an amino acid that, in excess, can damage blood vessel walls and increase the risk of heart disease