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Tirzepatide, sold as Mounjaro for diabetes and Zepbound for weight loss, is gaining popularity, offering promising clinical trial results with an average weight loss of 20%

Understanding these helps guide testing and treatment

This trial is ongoing and the results will provide robust evidence of the impact of various bariatric surgical procedures on long-term glycaemic control and T2DM remission [35, 36]

This suggests that the chemical modifications enhancing their stability may simultaneously limit their access to central GLP-1Rs