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Dapagliflozin doses of 5 or 10 mg per day in patients with type 2 diabetes mellitus for 12 weeks resulted in excretion of approximately 70 grams of glucose in the urine per day

(1998) administered male mice with -asarone at doses of 0, 10, 30 mg/kg per day for 5 days, and found that the failure rate of sperm implantation increased, and sperm aggregation and activity decreased, suggesting that -asarone had a direct toxic effect on sperm

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