Vitamin B12 shots are generally safe for most individuals, especially those with a B12 deficiency
Primary concerns include increased injection site reactions from multiple subcutaneous injections, difficulty attributing adverse effects to the correct agent, additional cost without proven benefit, and potential quality variability in compounded lipotropic products
However, not all interventions proved effective, as acetyl-L-carnitine plus alpha-lipoic acid failed to reverse insulin resistance in another NAFLD mouse model (32)
The resulting bioactive lipid vesicles protect active compounds, enhance bioavailability, accelerate absorption, improve cellular uptake, and support gastrointestinal comfort
Biomolecules 9(9):389 Lakshmanan Y et al (2024) Lycium barbarum glycopeptide promotes neuroprotection in ET-1 mediated retinal ganglion cell degeneration