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5A, S8), albeit lanifibranor demonstrated borderline statistical significance for improving fibrosis stage in GAN DIO-NASH-HCC mice (1 point improvement: vehicle 5/17 mice

The slices were rinsed and placed into a chamber embedded in the stage of an Olympus BX51WI microscope (Olympus) coupled to a 12-bit CCD fluorescent camera (SensiCam, PCO imaging)

Neural regeneration research 13(4):692 Chan KM, Gordon T, Zochodne DW, Power HA (2014) Improving peripheral nerve regeneration: from molecular mechanisms to potential therapeutic targets

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288 Existing studies have demonstrated that L-DON and JHU-083 can extensively inhibit Gln metabolizing enzymes and activate AMPK and c-Myc to inhibit glycolysis, thereby stopping tumor metabolic activity, alleviating hypoxia, and increasing the concentration of Gln and glucose in TME