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Some of these products have not undergone sufficient human clinical trials and may cause significant harm

doi: 10.1016/j.jid.2019.07.716

Sci Rep 9(1):18409 Sullivan LB, Martinez-Garcia E, Nguyen H et al (2013) The proto-oncometabolite fumarate binds glutathione to amplify ROS-dependent signaling

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(7) Studies have examined changes in oxygen consumption, substrate utilization, and thermogenesis following NNMT inhibition