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The reduction in IGFBP binding increases the bioavailable free fraction and extends the functional half-life of the molecule compared with native IGF-1

Central to ferroptosis is the dysregulation of iron metabolism, which is typically controlled by iron-regulatory proteins, such as transferrin and ferritin

In situ hydrogel based on Cu-Fe 3 O 4 nanoclusters exploits oxidative stress and the ferroptosis/cuproptosis pathway for chemodynamic therapy

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These include: iliotibial band (IT) syndrome, anterior knee pain syndrome, patellofemoral malalignment and chondromalacia patella