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Plant Physiol 169:01543.2015

The oxidative phase of the pentose phosphate pathway has long been considered the main pathway for the generation of cytosolic NADPH

39,44,47 In one crossover study, 47 homocysteine levels returned to baseline when NAC was stopped for the 1-month washout period, suggesting that effects are immediate and that NAC may need to be taken continuously to help maintain homocysteine levels