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[1] [2] This low introductory dose is intentional it allows the body to gradually adapt to the drug's pharmacological effects before the dose is escalated

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16(8) Shi Q, Wang Y, Hao Q, Vandvik PO, Guyatt G, Li J, Chen Z, Xu S, Shen Y, Ge L, Sun F, Li L, Yu J, Nong K, Zou X, Zhu S, Wang C, Zhang S, Qiao Z, Jian Z, Li Y, Zhang X, Chen K, Qu F, Wu Y, He Y, Tian H, Li S (2024) Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials

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