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Description

The trial enrolled 300 obese subjects (BMI 27-35 kg/m) across multiple centers and randomized them to AOD-9604 (3 mg subcutaneous injection once or twice daily) or placebo for 12 weeks

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As expected, in ligature induced experimental periodontitis, a considerable increase in vascular permeability in the gingival tissue was detected

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The present study clearly shows that BPC 157 is effective in ameliorating experimental periodontitis but further studies are needed to identify the exact mediators of this action

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